Intermediate filaments join the action
نویسندگان
چکیده
منابع مشابه
Intermediate filaments
Intermediate filaments form a class of insoluble cytoplasmic filaments ofdimensions intermediate in size between those of microtubules (about 25 nm in diameter) and microfilaments (about 7 nm in diameter). Thus, they are generally known as intermediate-sized filaments (IF)' or 10-nm filaments. They have been identified in virtually all differentiated types ofcells and it seems possible that IF-...
متن کاملIntermediate Filaments on the Move
In most vertebrate cells, intermediate filaments (IF) 1 form a continuous structural network extending from the nuclear surface to the cell periphery. Their unique viscoelastic properties render them more resistant than either microtubules or microfilaments to deformation and other external physical stresses. Through a growing family of associated proteins (IFAPs), IF are now known to be connec...
متن کاملNeuronal intermediate filaments.
Neurofilaments (NFs) are the most abundant structural components in large-diameter myelinated axons. Assembled as obligate heteropolymers requiring NF-L and substoichiometric amounts of NF-M and/or NF-H, NF investment into axons is essential for establishment of axonal caliber, itself a key determinant of conduction velocity. Use of transgenic mice to increase axonal accumulation of NFs or to e...
متن کاملIntermediate filaments in smooth muscle.
The intermediate filament (IF) network is one of the three cytoskeletal systems in smooth muscle. The type III IF proteins vimentin and desmin are major constituents of the network in smooth muscle cells and tissues. Lack of vimentin or desmin impairs contractile ability of various smooth muscle preparations, implying their important role for smooth muscle force development. The IF framework ha...
متن کاملIntermediate filaments in the human extraocular muscles.
PURPOSE To investigate the distribution of the intermediate filament (IF) proteins desmin, vimentin, and nestin in human extraocular muscles (EOMs). METHODS Healthy adult EOM samples were serially sectioned (5 and 1 μm) and processed for immunohistochemistry, with specific antibodies (Abs) against desmin, vimentin, and nestin and different myosin heavy chains (MyHCs), including the newly char...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2017
ISSN: 1538-4101,1551-4005
DOI: 10.1080/15384101.2017.1345230